Krista Dobi

Krista Carol Dobi

Assc Professor

Weissman School of Arts and Sciences

Department: Natural Sciences

Areas of expertise:

Email Address: krista.dobi@baruch.cuny.edu

Originally from New Jersey, Dr. Dobi did her graduate work at Harvard University, where she studied transcriptional regulation in yeast. After receiving her Ph.D. in Genetics in 2007, she spent several years as a postdoctoral fellow at Memorial Sloan Kettering Cancer Center in New York City, where she was the recipient of a NIH/Ruth L. Kirschstein postdoctoral fellowship to study transcriptional regulation of muscle development in Drosophila melanogaster. Dr. Dobi’s current research focuses on the formation of unique muscles during fruit fly embryonic development. In particular, she is interested in how muscles with distinct sizes, shapes, attachments and innervations are formed by the interplay of different transcription factors during development. She uses molecular, cellular and genetic approaches to understand basic questions of cellular specification.

Education

Ph.D., Genetics, Harvard University Cambridge MA

AB, Molecular Biology, Princeton University Princeton NJ

SemesterCourse PrefixCourse NumberCourse Name
Spring 2024BIO3005Molecular and Cellular Biology
Spring 2024BIO3005Molecular and Cellular Biology
Spring 2024BIO3005Molecular and Cellular Biology
Spring 2024BIO5000Independent Study Biology I
Fall 2023BIO3015Principles of Genetics
Fall 2023BIO3015Principles of Genetics
Spring 2023BIO5000Independent Study Biology I
Spring 2023BIO5000Independent Study Biology I
Spring 2023BIO3005Molecular and Cellular Biology
Spring 2023BIO3002Reading Science
Spring 2023BIO6002HHonors Biology II
Spring 2023BIO6003HHonors Biology III
Spring 2023BIO3005Molecular and Cellular Biology
Fall 2022BIO6001HBiology Honors I
Fall 2022BIO5001Independent Study Biology II
Fall 2022BIO6002HHonors Biology II
Spring 2022BIO5000Independent Study Biology I
Spring 2022BIO3005Molecular and Cellular Biology
Spring 2022BIO3005Molecular and Cellular Biology
Spring 2022BIO5000Independent Study Biology I
Spring 2022BIO6001HBiology Honors I
Fall 2021IDC3002HHon Sci & Tech NYC
Fall 2021BIOL70005Genetics: Lecture
Spring 2021BIO3005Molecular and Cellular Biology
Spring 2021BIO5001Independent Study Biology II
Spring 2021BIO3002Reading Science
Spring 2021BIO3005Molecular and Cellular Biology
Fall 2020BIO5000Independent Study Biology I
Fall 2020BIO3001Principles of Biology II
Spring 2020BIO3005Molecular and Cellular Biology
Spring 2020BIO3005Molecular and Cellular Biology
Spring 2020BIO5000Independent Study Biology I
Spring 2020BIO5000Independent Study Biology I
Spring 2020BIO6002HHonors Biology II
Fall 2019BIO6001HBiology Honors I
Spring 2019BIO3002Reading Science
Spring 2019BIO3005Molecular and Cellular Biology
Spring 2019BIO5000Independent Study Biology I
Spring 2019BIO3005Molecular and Cellular Biology
Fall 2018BIO3001Principles of Biology II
Spring 2018BIO3005Molecular and Cellular Biology
Spring 2018BIO3005Molecular and Cellular Biology
Spring 2018BIO5000Independent Study Biology I
Spring 2017BIO3005Molecular and Cellular Biology
Spring 2017BIO5000Independent Study Biology I
Spring 2017BIO3001Principles of Biology II
Spring 2017BIO3005Molecular and Cellular Biology
Spring 2017BIO5000Independent Study Biology I
Fall 2016BIO1003Survey of the Living World
Fall 2016BIO3001Principles of Biology II
Fall 2016BIO5000Independent Study Biology I
Fall 2016BIO1003Survey of the Living World
Spring 2016BIO5001Independent Study Biology II
Spring 2016BIO3005Molecular and Cellular Biology
Spring 2016BIO1015LFund Of Bio - Gen, Evol, & Eco
Spring 2016BIO3005Molecular and Cellular Biology
Fall 2015BIO1016Fundamentals of Biology
Fall 2015BIO1016Fundamentals of Biology
Fall 2015BIO5000Independent Study Biology I
Fall 2015BIO1015LFund Of Bio - Gen, Evol, & Eco
Fall 2015BIO1015LFund Of Bio - Gen, Evol, & Eco
Fall 2015BIO1015LFund Of Bio - Gen, Evol, & Eco

Journal Articles

Nowak, S. J., & Dobi, K. C. (2022). Taking Flight: An educational primer for use with "A Novel Mechanism for Activation of Myosin Regulatory Light Chain by Protein Kinase C-Delta in Drosophila". Genetics, 220(3).

Tessler, M., Gaffney, J. P., Oliveira, A. G., Guarnaccia, A., Dobi, K. C., Gujarati, N. A., Galbraith, M., Mirza, J. D., Sparks, J. S., Pieribone, V. A., Wood, R. J., & Gruber, D. F. (2020). A chordate luciferase described from a cosmopolitan tunicate shows convergent bioluminescence evolution across phyla. Scientific Reports, 10(1). 17724.

Dobi, K. C., Schulman, V. K., & Baylies, M. K. (2015). Specification of the somatic musculature in Drosophila. Wiley interdisciplinary reviews. Developmental biology, 4(4). 357-75.

Schulman, V. K., Dobi, K. C., & Baylies, M. K. (2015). Morphogenesis of the somatic musculature in Drosophila melanogaster. Wiley interdisciplinary reviews. Developmental biology, 4(4). 313-34.

Reavey, C. T., Hickman, M. J., Dobi, K. C., Botstein, D., & Winston, F. (2015). Analysis of Polygenic Mutants Suggests a Role for Mediator in Regulating Transcriptional Activation Distance in Saccharomyces cerevisiae. Genetics, 201(2). 599-612.

Dobi, K. C., Kumar, R. P., Baylies, M. K., & Abmayr, S. M. (2015). Muscle cell fate choice requires the T-box transcription factor midline in Drosophila. Genetics, 199(3). 777-91.

Dobi, K. C., Halfon, M. S., & Baylies, M. K. (2014). Whole-genome analysis of muscle founder cells implicates the chromatin regulator Sin3A in muscle identity. Cell reports, 8(3). 858-70.

Wong, M. C., Dobi, K. C., & Baylies, M. K. (2014). Discrete levels of Twist activity are required to direct distinct cell functions during gastrulation and somatic myogenesis. PloS one, 9(6). e99553.

Dobi, K. C., Metzger, T., & Baylies, M. K. (2011). Characterization of early steps in muscle morphogenesis in a Drosophila primary culture system. Fly, 5(2). 68-75.

Dobi, K. C., & Winston, F. (2007). Analysis of transcriptional activation at a distance in Saccharomyces cerevisiae. Molecular and cellular biology, 27(15). 5575-86.

Clark, I. E., Dobi, K. C., Duchow, H. K., Vlasak, A. N., & Gavis, E. R. (2002). A common translational control mechanism functions in axial patterning and neuroendocrine signaling in Drosophila. Development (Cambridge, England), 129(14). 3325-34.

Martin, S. G., Dobi, K. C., & St Johnston, D. (2001). A rapid method to map mutations in Drosophila. Genome biology, 2(9). RESEARCH0036.

Media Contributions

Dobi, K. C. (2016). Genes to Genomes Blog: No, Seriously: You Need an Individual Development Plan, (January 12).

https://genestogenomes.org/no-seriously-you-need-an-individual-development-plan/

http://genestogenomes.org/no-seriously-you-need-an-individual-development-plan/

Government Reports or Monographs

Dobi, K. C., & Kesarwala, A. H. (2021). Altered metabolism associated with muscle wasting during spaceflight.

Honor / AwardOrganization SponsorDate ReceivedDescription
Eugene M. Lang Faculty FellowshipBaruch College2018